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This technique can be used to enable genetic fatherhood to some men who have no spermatozoa in the ejaculate azoospermia and in whom spermatozoa cannot be obtained surgically from the testicles. This condition is called nonobstructive or secretory azoospermia, as opposed to obstructive azoospermia, in which complete sperm production does occur in the testicles, and potentially fertilizing spermatozoa can be obtained by testicular sperm extraction TESE and used for ICSI. In cases of nonobstructive secretory azoospermia, on the other hand, testicular sperm production is blocked at different stages of the process of sperm formation spermatogenesis. In those men in whom spermatogenesis is blocked at the stage of round spermatids, in which meiosis has already been completed, these round cells can successfully fertilize oocytes after being injected into their cytoplasm. Consequently, the distinction between round spermatids and other round cells of similar size, such as leukocytes, is not an easy task.
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Visible Embryo Carnegie Stage 2

A relatively minor point, though not trivial, has been the issue of the biological relatedness of the Jewish people, and their relatedness to the nations among whom they were resident. This particular point became more starkly relevant with a scientific understanding of human genealogy and genetic relationship in the 18th and especially 19th centuries, but its root can be traced back to antiquity. Jews are not simply a set of individuals who espouse a belief in the God of the Jews, or hold to the laws of the God of the Jews. Rather, one aspect of Jewish identity is its collective component whereby the adherents of the Jewish religion also conceive of themselves as a particular nation or tribe, and therefore bound together by a chain of biological descent. Of course these issues can not be understood except in light of a complex historically contingent sequence of events. Our understanding of what it means to be Jewish today, or the understanding of Jews themselves as to their own identity, is the outcome of a long process where self-identified Jews interacted with the broader milieu, as well as evolving in situ.
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Basic Genetics

The letter, at least initially, looked to be a bit of a letdown. And so it was with little fanfare that the Australian grandfather and retired cop tore the envelope open as he walked back to his car — at which point he stopped dead in his tracks. There could be only one reason for such a letter, he thought.
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Reduces androgen concentration by inhibiting gonadotropin secretion by the pituitary gland Decreases prostate size by decreasing cellular mass anemia, immunosuppression associated with repeated administration. Long-term use will increase prostate size and predispose to prostatic cysts, bacterial infections, and abscesses short-course therapy reduces prostatic secretory capability for 2 months Dihydrotestosterone DHT Receptor blockers anti-androgen flutamide blocks DHT produced from testosterone activity by competing for DHT receptors Decreases prostate size in dogs within 10 days to 6 weeks of treatment prostatic hyperplasia recurs within 2 months if treatment stopped. No effects on libido, sperm production or fertility in dogs. Progestins Megestrol acetate reduces serum testosterone concentration, inhibit DHT receptor binding, decreases DHT levels, and decreases the number of androgen receptors reduces prostate size and eradicates associated symptoms relapse in 10 to 24 months when treatment discontinued. No long-term studies on side effects on the dog.
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